Distribution of [14C]aztreonam in rat tissue

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Distribution of [14C]aztreonam in rat tissue.

[14C]aztreonam was administered intramuscularly (50 mg/kg) to male and female rats. Groups of 10 rats (five male and five female) were sacrificed at 0.25, 2, 6, and 24 h after dosing. Blood and various tissues were removed from six rats (three male and three female) in each group for determination of total radioactivity and unchanged aztreonam by liquid scintillation counting and thin-layer rad...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1984

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.26.2.127